Absorption of salicylic acid through the oral mucous membrane of hamster cheek pouch.
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چکیده
منابع مشابه
Carcinogenesis in the Hamster Cheek Pouch
Pouches from three experimental and one control animal were excised for analysis at various times during the first week and thereafter each week of carcinogen application (9,10-dimethyl-l ,~-benzanthracene) until the 131h week, at which time large tumors were present in all remaining aninmls. IIistologic progression from normal through inflanmmtion, uniform hyperplasia, localized premalignant h...
متن کاملPropagated vasodilation in the microcirculation of the hamster cheek pouch.
Propagated vasodilation has been observed in the peripheral vasculature and may be significant in integrating the behavior of terminal arterioles and larger vessels. We have studied the characteristics of propagated vasodilation induced by acetylcholine in the microcirculation of the cheek pouch of the golden hamster. The technique of microionophoresis was used as a means of achieving relativel...
متن کاملSpontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster
A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...
متن کاملBoron neutron capture therapy for the treatment of oral cancer in the hamster cheek pouch model.
We have proposed and validated the hamster cheek pouch model of oral cancer for boron neutron capture therapy (BNCT) studies and shown that boronophenylalanine delivers potentially therapeutic 36.9 +/- 17.5 ppm boron to tumor tissue with tumor:normal tissue and tumor:blood ratios of 2.4:1 and 3.2:1, respectively. Here we report the first evidence of the usefulness of BNCT for the treatment of o...
متن کاملEffects of tetraiodothyronine and triiodothyronine on hamster cheek pouch microcirculation.
The aim of the present study was to assess the effects of topically applied triiodothyronine (T(3)) and thyroxine (T(4)) on the arterioles of hamster cheek pouch microcirculation in vivo. Microvessels were visualized using a fluorescent microscopy technique. Topical application of T(3) (3.08, 30.8, 61.5, 307, 615, and 6,150 nM/l) consistently induced dose-dependent dilation of arterioles within...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1980
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.28.1056